On the Trap Space Semantics of Normal Logic Programs
The logical semantics of normal logic programs has traditionally been based on the notions of Clark’s completion and two-valued or three-valued canonical models, including …
The logical semantics of normal logic programs has traditionally been based on the notions of Clark’s completion and two-valued or three-valued canonical models, including …
We analyzed publicly available single-cell RNA sequencing data (GEO accession GSE147424) derived from human skin biopsies of lesional and non-lesional atopic dermatitis samples …
The regular models of a normal logic program are a particular type of partial (i.e. 3-valued) models which correspond to stable partial models with minimal undefinedness. In this …
Chemical Reaction Networks (CRNs) are a standard formalism used in chemistry and biology to model complex molecular interaction systems. In the perspective of systems biology, …
Boolean Networks (BNs) are widely used as a modeling formalism in several domains, notably systems biology and computer science. A fundamental problem in BN analysis is the …
Boolean Networks (BNs) are an efficient modeling formalism with applications in various research fields such as mathematics, computer science, and more recently systems biology. …
Boolean modelling of gene regulation but also of post-transcriptomic systems has proven over the years that it can bring powerful analyses and corresponding insight to the many …
The Turing completeness result for continuous chemical reaction networks (CRN) shows that any computable function over the real numbers can be computed by a CRN over a finite set …
In this short paper extracted from [7], we present a polynomialization algorithm of quadratic time complexity to transform a system of elementary differential equations in …
Chemical reaction networks (CRNs) are a standard formalism used in chemistry and biology to reason about the dynamics of molecular interaction networks. In their interpretation by …
Chemical Reaction Networks (CRNs) provide a useful abstraction of molecular interaction networks in which molecular structures as well as mass conservation principles are …
With the automation of biological experiments and the increase of quality of single cell data that can now be obtained by phospho-proteomic and time lapse videomicroscopy, …
With the automation of biological experiments and the increase of quality of single cell data that can now be obtained by phosphoproteomic and time lapse videomicroscopy, …
BIOCHAM-4 is a tool for modeling, analyzing and synthesizing biochemical reaction networks with respect to some formal, yet possibly imprecise, specification of their behavior. We …
Poster
Automating the process of model building from experimental data is a very desirable goal to palliate the lack of modellers for many applications. However, despite the spectacular …
Experimental observations have put in evidence autonomous self-sustained circadian oscillators in most mammalian cells, and proved the existence of molecular links between the …
In Systems Biology, modelers develop more and more reaction-based models to describe the mechanistic biochemical reactions underlying cell processes. They may also work, however, …
Experimental observations have put in evidence autonomous self-sustained circadian oscillators in most mammalian cells, and proved the existence of molecular links between the …
Constraint programming is traditionally viewed as the combination of two components: a constraint model and a search procedure. In this paper we show that tree search procedures …